In Children with 46, XY DSD; HCG Testing is not always the Best Answer for Testicular Function Assessment

Hormonal levels are the hallmark for assessment of testicular function in XY DSD (Disorders sex development). Traditionally, it has relied on testosterone level increment after hCG (human Chorionic Gonadotropin) stimulation testing. More recently role Sertoli cell hormones is more emphasized. Objectives: Evaluating serum anti-mullerian hormone and inhibin B pre-pubertal testis without need test. Method: The study was conducted Endocrinology Clinic Alexandria University Children’s Hospital. All patients who present with were tested Testosterone (T), Dihydrotestosterone (DHT), Follicle Stimulating Hormone (FSH), Luteinizing (LH), Anti-Mullerian (AMH), B. cases had Results: test done 32 cases. There significant positive correlation between before (p <0.001). Similarly, identified basal AMH <0.001) (MCp= 0.025). Conclusion: Single measurement and/or can detect presence testes by a reliable non-invasive way. Basal an important tool to distinguish cryptorchidism anorchia. needed work-up inconclusive results.